Fast-acting nausea relief
Typical Cost
$25–$50 (as add-on)
Duration
Added to IV drip or 2-minute injection
Ideal For
Hangover nausea, stomach bugs, motion sickness, add-on to any drip
Zofran (ondansetron) is a prescription anti-nausea medication originally developed for chemotherapy patients. It works by blocking serotonin receptors in the gut and brain that trigger nausea and vomiting. As an IV or IM injection, it works significantly faster than oral tablets — providing relief within minutes. It's a standard component of hangover relief IVs and is also available as an add-on to any drip.
Based on 100 clinics with published pricing
Lowest
$10
Median
$30
Average
$65
Highest
$349
When added to an IV drip, Zofran typically works within 5 to 10 minutes. As a standalone injection, relief comes within 15 to 20 minutes. The most common side effect is a mild headache. It's safe for most adults but should be used with caution in people with certain heart conditions.
Ondansetron 4mg — a serotonin 5-HT3 receptor antagonist
Top cities where zofran (anti-nausea) is offered
200 clinics found with pricing data
4480 General De Gaulle Dr · New Orleans, LA
Inside Vanishing Ink Med-Spa & Wellness, 8190 W Union Hills Dr ste 145 · Glendale, AZ
231 Ruby Ave suite d · Kissimmee, FL
8355 Cherokee Blvd Suite 201 · Douglasville, GA
2100 S Main St B · Ann Arbor, MI
11010 Metcalf Ave · Overland Park, KS
13954 W Waddell Rd ste 103 168 · Surprise, AZ
1225 Timberhurst Trail · Fort Worth, TX
2240 Palm Beach Lakes Blvd Suite 301 · West Palm Beach, FL
820 W 41st St Suite 309 · Miami Beach, FL
660 Arlington Creek Centre Dr Building 4 Suite C · Baton Rouge, LA
13434 Leopard St Unit A 10 · Corpus Christi, TX
4900 Gaviota Ave · Long Beach, CA
201 E Academy St Suite 108 · Fuquay-Varina, NC
336 Cove Terrace Shopping Center · Copperas Cove, TX
5401 104th St E c · Puyallup, WA
981 Hackler St Unit D · Myrtle Beach, SC
28677 Old Town Front St Suite F · Temecula, CA
350 Newnan Crossing Bypass · Newnan, GA
2300 Newport Blvd · Costa Mesa, CA
14694 Orchard Pkwy #225a · Westminster, CO
1451 W Cypress Creek Rd #300 · Fort Lauderdale, FL
490 Post St Floor 12, Ste. 1233 · San Francisco, CA
850-A S Lake Dr · Lexington, SC
12850 Alpharetta Hwy Suite 1200 · Alpharetta, GA
300 SE 2nd St Suite 643 · Fort Lauderdale, FL
14330 S Padre Island Dr Suite 114 · Corpus Christi, TX
36483 Perkins Rd Ste. A · Prairieville, LA
315 Riverside Pkwy NE Suite 190 · Rome, GA
133 N Chalkville Rd Suite 1 · Trussville, AL
2615 George Busbee Pkwy NW #5 · Kennesaw, GA
Inside of Cowboys Fit, 1401 Town Center Dr · Pflugerville, TX
6909 Orchard Lake Rd · West Bloomfield Township, MI
1750 Marietta Hwy Suite 220 · Canton, GA
4200 Northside Pkwy NW building 8 suite 300 · Atlanta, GA
769 Bandit Trail · Keller, TX
150 Sunny Isles Blvd · Sunny Isles Beach, FL
4444 Corona Dr Ste 111 · Corpus Christi, TX