The Short Answer
Somewhere between $75 and $800, depending on what's in the bag. That range isn't a dodge — it reflects genuinely different products. A basic saline hydration drip and a full-dose NAD+ infusion share a delivery mechanism and not much else. One uses a commodity solution that costs a clinic a few dollars per bag and takes twenty minutes. The other uses an expensive molecule sourced from a licensed compounding pharmacy and requires a nurse's time for two to four hours. The price difference is mostly explained by those facts.
Most people searching this question are trying to figure out whether IV therapy is accessible before committing to an appointment. The common treatments — hydration drips, Myers' Cocktails, vitamin shots — land in a range that's in the same territory as a massage or a physical therapy copay. The specialty infusions cost more, and the reasons are legitimate. Here's how the numbers break down.
What Goes Into the Price
Four things drive IV therapy pricing, and none of them is pure margin.
The ingredients. A basic saline drip uses a commodity solution — IV-grade sodium chloride — that costs a clinic a few dollars per bag. A 1,000mg NAD+ infusion uses a molecule that's temperature-sensitive, must come from a licensed 503B compounding pharmacy, and costs meaningfully more to source. The ingredient cost alone explains a significant portion of the gap between the cheapest and most expensive treatments on any clinic's menu.
Nursing time. Every IV session requires a licensed nurse or another credentialed professional to insert the catheter, monitor the infusion rate, manage any side effects, and remove the line. A twenty-minute hydration drip uses less of that person's time than a three-hour NAD+ session. Most clinics price accordingly, and that's appropriate — you're not just paying for fluids, you're paying for a clinical procedure administered by a licensed professional.
Prescription add-ons. Hangover relief IVs and migraine protocols often include ondansetron (Zofran) for nausea and ketorolac (Toradol) for pain — both prescription medications that require a licensed prescriber to authorize and a legitimate pharmacy to supply. When included as standard components of a protocol, these add cost and, when done properly, add a layer of medical oversight that justifies the price. Some clinics list them as optional add-ons; others build them in. Worth checking before you compare sticker prices between providers.
Overhead. A clinic in Midtown Manhattan operates under different rent, staffing, and insurance costs than one in suburban Ohio. These costs hit the menu price in ways that have nothing to do with formulation. It's real, and it's one reason why location shapes what you'll pay more than almost any other factor.
Prices by Treatment Type
These ranges are based on pricing data collected from clinics across the US through this directory. They reflect what real providers are charging in 2026, not manufacturer suggested prices.
Basic Hydration Drip: $75–$150. Pure saline or Lactated Ringer's, sometimes with electrolytes added. The simplest and most affordable treatment available. Sessions run 20–30 minutes. This is what urgent care and emergency rooms deliver when you're dehydrated — delivered in a more comfortable setting, on your schedule.
Myers' Cocktail: $150–$300. The most widely offered multi-nutrient infusion in the country. The standard formula includes magnesium, B vitamins, vitamin C, and calcium in saline, though the specific doses vary considerably between providers. Higher magnesium doses, more vitamin C, or premium B12 forms like methylcobalamin push prices toward the top of the range. At the low end, you may be getting a lighter formulation — worth asking before booking.
Immunity Boost: $150–$275. Builds on the Myers' framework with higher vitamin C concentration — typically 5 to 10 grams or more — plus zinc and sometimes selenium. Takes 30–45 minutes.
Hangover Relief: $150–$300. The premium over a basic hydration drip reflects the prescription components. A properly composed hangover protocol adds ondansetron for nausea and ketorolac for inflammation and pain — both of which require medical authorization and legitimate pharmacy sourcing. Clinics that include both as standard components will price this toward the upper end. If a clinic is offering hangover IVs at $80, either the prescription components are missing or something else is off.
Glutathione Push: $50–$100 as an add-on, $100–$175 standalone. Usually appended to the end of another drip, taking advantage of the line already in place. As a standalone, it's a 10–15 minute slow IV injection. The price reflects the compounded glutathione, not the brevity of the session.
B12 Shot: $25–$50. The most affordable treatment at most clinics. Intramuscular injection, under five minutes. Many clinics bundle these into packages of four to six shots at a discount. This is a legitimate, evidence-supported treatment — B12 deficiency is common and oral supplements often don't address it adequately in people with absorption issues.
Vitamin D Shot: $25–$75. Similar format to B12 — quick intramuscular injection. Oil-based solution provides slow-release delivery over several weeks.
Athletic Recovery Drip: $150–$300. Typically combines saline with amino acids, magnesium, B vitamins, and vitamin C. Similar price range to the Myers' Cocktail, with the ingredient mix oriented more toward muscle recovery than general wellness.
NAD+ Therapy: $250–$800. The most expensive commonly available IV treatment, and the cost reflects what's behind it. The molecule itself is expensive and must come from a licensed compounding pharmacy. Sessions run 2–4 hours — sometimes longer — requiring sustained nursing oversight. The dose range (250mg to 1,000mg per session) explains most of the price variation you'll see between clinics. A $250 NAD+ infusion at 250mg and an $800 infusion at 1,000mg aren't competing on quality; they're different quantities of the same thing. Ask specifically what dose you're getting before comparing prices.
Semaglutide/GLP-1 Programs: $300–$600/month. Not an IV, but increasingly offered at the same clinics. Compounded semaglutide is significantly cheaper than brand-name Ozempic or Wegovy. The monthly cost typically includes medication, clinic management fees, and follow-up support.
How Location Changes the Number
The same Myers' Cocktail costs more in Los Angeles than in Lexington. That's true, it's not a surprise, and it's not entirely explained by profit motive. Commercial rent, licensed nursing salaries, malpractice insurance, and local market dynamics all vary by region — and they all flow into the menu price.
Markets where IV therapy skews expensive: New York, Los Angeles, Miami, San Francisco, Chicago, Las Vegas, and most major coastal metros. Markets where you'll generally pay less: mid-size inland cities, smaller metro areas, and regions where the cost of operating a clinic is lower.
What location shouldn't tell you is much about quality. A $270 Myers' Cocktail in Manhattan isn't inherently a better formulation than a $160 one in Nashville. If price is a real factor in your decision, comparing what's actually in the bag — specific doses of magnesium, vitamin C, and B12, where the formulation is sourced — tells you more than the geography of the clinic.
The Mobile IV Markup
Mobile IV services — which dispatch a nurse to your home, hotel, or office — typically add $50 to $100 to the base treatment price. That surcharge covers the travel time, logistics, and the premium on the nurse's schedule.
Whether it's worth the extra is straightforward to reason about. For hangover recovery, the math is usually obvious: when you're genuinely nauseated and your head is pounding, $75 to not have to get in a car is a reasonable transaction. For routine wellness infusions when you're fully functional, going to the clinic almost always saves money without sacrificing anything clinically meaningful.
One thing mobile services don't advertise clearly: availability is tighter. A clinic has a team; a mobile service is booking a single nurse's schedule. Saturdays after major events, holiday weekends, and the hours between 8 and 11am in tourist-heavy cities fill up fast. If timing matters, book ahead.
Memberships: When the Math Works
Most IV therapy clinics offer some form of membership or package pricing — typically a monthly fee covering one or two sessions at 15–30% off the walk-in rate, sometimes with free add-ons like B12 shots included.
The math works if you're planning to go at least once a month consistently. At a $175 walk-in Myers' Cocktail and a 20% membership discount, you break even after the first session and save $35 on every visit after that. If you're going six times a year, you're not getting the savings a monthly membership promises — and if there's a monthly minimum, you may end up paying for sessions you didn't take.
Things worth checking before signing up: whether unused sessions roll over, how cancellation works (some require 30 days' notice, some lock you in for three to six months), and whether the membership is genuinely tied to a discount or just a repackaging of the same price. Some clinics call a slightly discounted single-session rate a 'membership' — the label doesn't mean much on its own.
What Good Value Looks Like
At the low end of the price spectrum, unusually cheap IV therapy usually signals one of a few things: lower doses than the market standard, less experienced nursing staff, unclear sourcing of compounded ingredients, or minimal medical oversight. The ingredient cost alone makes certain price points implausible for a legitimately run clinic. A Myers' Cocktail at $89 delivered by a licensed nurse using properly sourced compounded magnesium and methylcobalamin B12 doesn't pencil out. Something in that picture is different from what you're imagining.
At the high end, a $350 Myers' Cocktail isn't inherently better than a $175 one unless you can identify a specific formulation difference. Some of the premium at luxury wellness clinics reflects the spa-like setting, concierge booking experience, and ambient aesthetic — not the contents of the IV bag. That's a legitimate choice to make, but it should be a deliberate one.
The signal worth looking for isn't a particular price point — it's a clinic that can tell you specifically what's in the bag, at what dose, sourced from where, administered under whose medical oversight. Any clinic that's confident in the quality of what they're providing answers those questions without hesitation.
Questions to Ask Before Booking
A few specific questions separate clinics worth trusting from ones worth skipping, regardless of price.
What's in the bag, and at what dose? 'Myers' Cocktail' is a category, not a standardized recipe. A clinic should be able to tell you the magnesium dose, the vitamin C concentration, and what form of B12 they use. If they can't or won't, that's information.
Where is the formulation sourced? IV solutions should come from a licensed 503B outsourcing facility or a state-licensed compounding pharmacy with appropriate quality controls. This is basic patient safety. Any reputable clinic can answer this.
Who provides medical oversight? A physician, nurse practitioner, or physician assistant should be the medical director overseeing protocols, even if a registered nurse administers the infusion. Ask who that person is. If there's no clear medical oversight structure, the price doesn't matter — find a different clinic.
Is there an intake process? A real intake form covering current medications, relevant health history, and any contraindications should happen before your first appointment. It's not bureaucracy — it's the clinic confirming you're an appropriate candidate for what you're getting. Skipping it is a red flag at any price point.